Percutaneous vertebral puncture biopsy and MRI are useful in diagnosis of malignant vertebral fractures

This study is to investigate the clinical application of percutaneous vertebral puncture biopsy and MRI in diagnosis of malignant vertebral fractures. A total of 46 patients were enrolled in this study. Percutaneous kyphoplasty was performed for each patient. The coaxial puncture biopsies in broken spines were conducted. The pathological results were compared with the magnetic resonance imaging (MRI) results. The MRI scan showed that there were 67 possible malignant vertebral fractures in 46 patients. Among the 67 possible malignant vertebral fractures, 64 were successfully confirmed by pathological examination. The successfulness and positive rates in biopsy were 95.52% and 76.56%, respectively. No complication occurred. Kappa analysis indicated that preoperative MRI for malignant vertebral fracture was consistent with biopsy. Percutaneous vertebral puncture biopsy and MRI are useful in diagnosis of malignant vertebral fractures.